NeuroStar delivers our advanced and unique form of TMS (transcranial magnetic stimulation), a non-invasive therapy that uses targeted magnetic pulses to stimulate areas of the brain that are underactive in people suffering from depression. Because SeattleNTC has been providing TMS for our patients since 2008, we are the most experienced and trusted provider in Washington state. Tel: (503) 342-7460. I was sad and miserable all the time. Transcranial Magnetic Stimulation (TMS) involves a series of short magnetic pulses directed to the brain to stimulate nerve cells. Suite 102. The woman’s husband was Brian Johns, M. 3 people like this. "In a clinical setting, treatment with the SAINT system brought rapid remission or a significant reduction of depression symptoms, to 79% of participants with severe depression in a double-blinded randomized clinical trial. Regular TMS has only 1 treatment a day, with longer sessions, 20 to 45 minutes. REQUEST A CONSULTATION. The neuromodulation. A promising new treatment for depression 07:36. , of Stanford University, and colleagues. 5% of severely depressed patients to full freedom from depressiby cafermed Psychiatrist (Verified) SAINT TMS 79% effective for severe depression. A New Kind of TMS for Depression: SAINT Becomes Stanford Neuromodulation Therapy (SNT) — The Psychiatry Resource. 13. Senova et al. Summary: Transcranial magnetic stimulation (TMS), a treatment involving strong magnetic pulses applied to the scalp, alleviates severe depression by reversing the flow of neural activity in the brain. Auburn (916) 351-9400; Elk Grove. Birmingham, AL Office (205) 968-1227. TMS is a noninvasive procedure that uses magnetic fields to stimulate certain parts of the brain to improve symptoms of depression. The FDA has approved a six-week TMS protocol for treating depression. Beat depression in FIVE days. It is a form of transcranial magnetic stimulation, which is approved by the Food and Drug Administration for treatment of depression. (904) 495-7103. During TMS therapy, a device that generates a magnetic field is used to induce electrical currents in the brain. Food and Drug Administration (FDA). 9% lost response during the first six months post treatment. TMS uses a targeted magnetic pulses, similar to what is used. Discover our revolutionary 5-day depression treatment plan. Quick Links. Our kind and caring staff is ready to walk you through our process along with any other questions you might have. ”. Book an appointment today!Key Points. 66. FOR IMMEDIATE RELEASE: Ashleigh Servadio, MSC. With the 510. 2005). to feel better. 1350 Old Bayshore Highway. It is used to treat mental health disorders, particularly. Please call (844) 867-8444 or book an appointment. Treatment is given through repetitive magnetic pulses, known as repetitive TMS. Dr. Those suffering from depression and anxiety in the Seattle-Northgate region turn to NeuroStim TMS first for TMS and other non-invasive treatment. 7405 Shallowford Rd. treatment resistant depression pati ents who did not respond t o acute TMS treatment responded after four weeks o f twice weekly deep TMS in the Brainsway pivotal tri al. Food and Drug Administration for treatment-resistant depression. In 1985, Anthony Barker and his team developed transcranial magnetic stimulation (TMS) when they produced a motor response by noninvasively applying a magnetic field to the human motor cortex. Intermittent theta-burst stimulation (iTBS) is a noninvasive brain stimulation treatment that has been approved by the U. A total of eight articles involving 566 patients were included. Psychol Med. How TMS Treatment Can Calm Your Mood Swings. 29 study in which the treatment was found to have induced remission in nearly 80% of participants. Howard has particular interests in treatment of depression and suicide prevention. Treatment-resistant depression (TRD) is prevalent and associated with a substantial psychosocial burden and mortality. 6, 2022 — Magnus Medical, Inc. We are now the largest and most advanced TMS clinic in. CNY TMS Psychiatry specializes in treating both FDA-approved and 'off-label' conditions using transcranial magnetic stimulation, a safe. SAINT is 90,000 pulses to the brain in one week, spaced precisely to ensure that your brain learns the lesson most robustly. S. Transcranial magnetic stimulation (TMS) is a way of treating severe depression when other treatments haven’t worked. 17 St John’s. TMS is also effective for those with anxiety, OCD, PTSD,. There were no significant differences for response (p = 0. Most patients find TMS. For many people who are experiencing depression, the condition is both debilitating and life-altering. Introduction. Transcranial Magnetic Stimulation (TMS) Resources. Nearby Areas. Requesting transcranial magnetic stimulation (TMS) office information Physician n ame: Phone #:. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and promising treatment for depression that has been approved by the U. Suite 43. A new type of magnetic brain stimulation brought rapid remission to almost 80% of participants with severe depression in a study conducted at. We provide Transcranial Magnetic Stimulation (TMS) Leading Edge Technology for Medication Resistant Depression. If medications and therapy are not enough for your depression, approach TMS therapy confidently. She enjoys working alongside patients on their path to improved quality of life. Food and Drug Administration for the treatment of treatment-resistant depression but is limited by suboptimal efficacy and a 6-week duration. (the manufacturer of the product) announced Tuesday. Reading time: 5 minutes. Traditional TMS treatment typically takes 6-7 weeks, whereas Kaizen Brain Center’s Accelerated TMS program dramatically reduces the treatment period to just 5 days. Available both in-person and online. Offering treatment options for treatment resistant depression and other conditions in both Halifax, Nova Scotia & Fredericton, New Brunswick. To summarize the current evidence for its efficacy, we reviewed clinical trials from the last 20 years that investigated TMS for positive symptoms. (67. TMS stands for “transcranial magnetic stimulation. SAINT Depression Treatment. Inspire TMS Denver offers discounted pricing and packages for Accelerated TMS to make sure that this burgeoning treatment is more accessible to our patients. 2017;10(4. Teresa Lindhardt, 55, had major depressive disorder, also called clinical depression. iTBS delivers a standard TMS treatment in a shorter. Accelerated TMS (aTMS) protocols address these burdens and attempt to increase the efficiency of standard T. It could also help for OCD, anxiety, and PTSD. The average remission time is one year, providing lasting relief for those struggling with treatment resistant conditions. Available in-person. Numerous studies have been conducted on the use of TMS in a variety of conditions, and there are meta-analyses for. In the late 1990’s physicians began to explore the. TMS Maine provides Transcranial Magnetic Stimulation therapy for treatment-resistant depression, conveniently located in South Portland, Maine and servicing all of Northern New England. Post-traumatic stress disorder (PTSD) is a debilitating psychiatric disorder. Secondary outcomes were change in continuous and categorical outcomes on self-report depression scales (9-Item Patient Health Questionnaire [PHQ-9], and Inventory of Depressive Symptoms-Self. We specialize in Medication Management, Anxiety, and Depression. 090, P = 0. Book an appointment today!Few studies have examined the effectiveness of transcranial magnetic stimulation (TMS) in real-world clinical practice settings. Recent methodological advances suggest that the. Transcranial magnetic stimulation (TMS) can be a safe and effective choice for the treatment of depression. OPEN. Port Saint Lucie, FL 34986. At CenterPointe Hospital, we offer transcranial magnetic stimulation (TMS) for adults who are struggling with medication-resistant depression. Findings In this randomized noninferiority trial of 172 participants, improvement on the primary clinical measure (Montgomery-Åsberg Depression Rating. The neuromodulatory technique rTMS is a treatment method approved by the United States Food and Drug Administration for patients with major depressive disorder that has not. The new SAINT TMS protocol is a revolutionary new solution for helping those with Treatment-Resistant Depression. Electrodes are implanted in specific regions targeting the underlying cause of the disease. 1–4 The strongest evidence-based treatments for MDD during pregnancy are psychotherapy and. Anchorage, AK, 99508. Some TMS facilities can do bilaterial treatment (meaning both sides of your head, LDPFC and RDPFC). (Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression) on 22 patients. Effectiveness and acceptability of accelerated repetitive transcranial magnetic stimulation (rTMS) for treatment-resistant major depressive disorder: an open label trial. A core feature of this program is the precise targeting of the depression area, identified using. Prefrontal TMS therapy repeated daily for four to six weeks is a. 1/2 Orange St. Dr. They suggest the treatment normalizes connectivity between the amygdala, insula, and medial frontal gyrus, and that is the general consensus of earlier. We all know how difficult treatment resistant depression (TRD) is for both the patient and the clinician. Our reputation, results, and standard of care make us the obvious choice, even for patients with longstanding, stubborn depression and anxiety that is resistant to other forms of treatment. TMS is non-invasive; it is administered at the doctor’s office and does not require anesthesia. S. The preliminary evidence suggests connectivity between the amygdala, insula, and medial frontal gyrus is altered in a meaningful way resulting in the improvement in depressive symptoms. SAINT TMS Pasadena. For example, one study on Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) TMS for treatment-resistant depression had 90% of participants meet remission criteria after treatment. Port Saint Lucie, FL 34986. Dr. During ECT, an electrical current induces a brief seizure. The treatment uses precise targeting. Cassidy has worked tirelessly in creating fast and convenient access to mental health treatment. July 18, 2023. TMS utilizes MRI strength magnetic pulses to stimulate areas of the brain known to be hypoactive in patients with depression. At the planned interim analysis, results showed that patients treated with SAINT achieved a 52. Stanford researchers optimized an FDA-approved form of non-invasive magnetic brain stimulation to better treat treatment-resistant depression. VNS or Vagus Nerve Stimulator. In this small open-label study testing the new Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) in patients with depression, 84% of the participants met the criteria for remission (defined as a score of 10 or less on the Montgomery-Åsberg Depression Rating Scale, or MADRS) after five days. org to schedule an appointment and learn more. Location. Effect of repetitive. This led to a severe depression. ” The American Journal of Psychiatry (First published online: April 07, 2020) DOI: 10. The first report of its effectiveness is very encouraging. , 2016). Ben van der Meer | Sacramento Business JournalArticle Abstract Objective: To evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) in patients with major depressive disorder (MDD) and 2 or more prior antidepressant treatment failures (often referred to as treatment-resistant depression ). Time period. Research indicates that this brain region is underactive in depression. One option. Now, scientists claim they've developed a targeted, faster form of TMS for severe depression. The Food and Drug Administration (FDA) in September cleared the SAINT Neuromodulation System for the treatment of refractory depression in adults. If future research replicates these astonishing results, SAINT could be a game-changing therapy for treatment-resistant depression. This review aims to describe the large, randomized controlled studies leading to the modern use of. TMS treatment involves stimulating underactive areas of the brain with brief magnetic pulses. Cole, Katy H. 58 N 9th St. NeuroStim TMS Everett. The abnormal flow of neural activity found in many depressed patients can potentially. com. She has achieved board certification in Psychiatry,. OBJECTIVE: Transcranial magnetic stimulation (TMS) is a noninvasive and easily tolerated method of altering cortical physiology. There are few prior studies of interventions for TRD in adolescents. Franklin, TN (615) 656-3380 CTMSS Press Release: Regarding FDA Clearance of SAINT Neuromodulation System. Harvard Health Publishing: “Transcranial magnetic stimulation (TMS): Hope for stubborn depression. Mid City TMS is a transcranial magnetic stimulation (TMS) center at the forefront of treatments for depression, located at 280 Madison Avenue in NYC. SAINT depression treatment got FDA-clearance in September 2022. Though the above options could be helpful for patients suffering from mild to moderate depression, these might not be strong enough to combat severe depression. TMS has become a promising treatment alternative for the estimated 30 percent to 50 percent of people with depression who don't respond sufficiently to antidepressant medications. Practice at a Glance. Food and Drug Administration (FDA), it has been available to people whose depression has resisted conventional forms of treatment. Scenic City Neurotherapy Ketamine & TMS. Conditions Treated with TMS;. According to Magnus, the SAINT™ Neuromodulation System “uses structural and functional magnetic resonance imaging (MRI) to inform a proprietary algorithm that identifies the optimal anatomic target for focused. We help people suffering from depression, anxiety, and other mental health or neurological conditions. 1100 Main St. The SAINT™ Neuromodulation system has recently received FDA clearance, marking a significant milestone in the field of medical technology. Cost/Insurance. In her garden outside San Francisco, Deirdre Lehman tries to keep her demons at bay. TMS is FDA-approved to treat. The American Journal of Psychiatry published results from a double-blinded RCT evaluating SAINT last year, showing that 79% of people in the active treatment arm entered remission from their depression compared to 13% in the sham treatment arm. A POTENTIAL FASTER, MORE EFFICIENT TREATMENT METHOD: INTERMITTENT THETA BURST STIMULATION (ITBS) An emerging method of excitatory TMS, called intermittent theta-burst stimulation (iTBS), is a potentially faster, more efficient treatment for depression. 315-671-2140. Portland, OR, 97232. Florida Center for TMS, Psychiatrist, Saint Augustine, FL, 32086, (904) 780-5829, Florida Center for TMS is a specialized psychiatry clinic that specializes in Transcranial Magnetic Stimulation. NeuroStim TMS Everett. Psychiatry researchers are embarking on a pilot study to learn if a novel form of transcranial magnetic stimulation (TMS) can yield more rapid improvements for patients with treatment-resistant depression in the setting of a bipolar 1 disorder diagnosis. Thirty percent of patients with treatment-resistant depression (TRD) obtain remission with conventional. Williams is a 2018 and 2016 BBRF Young Investigator and winner of the 2019 BBRF Klerman Prize for. A derivative of the drug; Ketamine. TMS has been. Abbott reinvigorates DBS trials for major depression. . Arulpragasam2,3, William M. Advanced therapies for depression. Resting-state functional MRI was used to. The department offers: Experience. Before the use of TMS, he said, “people would either suffer in silence or try medication trial after medication trial, with no success. 706. Find top doctors who perform Depression Management near you in Auburn, AL. Contact Us Today! Don’t wait to find help for your mental illness. It has been definitively proven that transcranial magnetic stimulation (TMS) is an effective treatment for treatment-resistant depression. Clinical studies showed that one in two patients who had TMS had significant improvement in. com. Ziegler has been out as he’s been having some battles with mental health. 19 January 2022. The overall treatment response rate was 43. Repetitive transcranial magnetic stimulation (rTMS) is an FDA-approved noninvasive brain stimulation treatment for TRD but is limited by low efficacy and 6-week treatment duration. TMS is Transcranial Magnetic Stimulation therapy, a proven treatment for major depression. A new option for people with treatment-resistant depression and anxiety will be available on the Big Island starting Monday. Find top doctors who perform Depression Management near you in Auburn, AL. Suite 601. Hours: Monday-Friday, 9am-6pm. Transcranial magnetic stimulation has now been an FDA-approved treatment for depression for 14 years. On July 12, 2022 Abbott announced that the FDA has granted Breakthrough Device Designation for its plan to investigate the use of its deep brain stimulation system in treatment-resistant depression (TRD), a form of major depressive disorder (MDD). Fax: 916-567-3501. If a person has treatment-resistant depression, a doctor may. Schutter DJ. TMS targets the activity of nerve cells in your brain, which may help with depression. Enter state to find the closest providers. 928. known as SAINT. Methods: Twenty-two participants with treatment-resistant depression received open-label SAINT. Headaches. You deserve. The FDA gave its blessing to the Saint system from Magnus Medical, which uses patient scans to direct neurostimulation therapy to the area of the brain where it may be most effective. Since the 1980s, TMS has been used to study the nerve fibers that carry information about movements from the brain to the spinal cord and onto the muscles. Introduction. A New Kind of TMS for Depression: SAINT Becomes Stanford Neuromodulation Therapy (SNT) — The Psychiatry Resource. TMS can only directly stimulate the outermost layer of the brain, but a recent study by researchers at. A summary of TMS for depression. TMS is a noninvasive procedure using magnetic fields to stimulate nerve cells, or neurons, in the brain. TMS is an FDA-cleared, non-drug, non-invasive therapy for the treatment of Major Depressive Disorder (MDD) and Obsessive-Compulsive Disorder (OCD). If depression fails to lift, the next line of treatment for some may be a noninvasive form of brain stimulation called transcranial magnetic stimulation (TMS) that is helpful in certain cases and has very few side effects. Cleared by the US Food and Drug Administration (FDA), TMS uses short, magnetic pulses to stimulate underactive nerve cells in brain regions known to regulate. We specialize in Medication Management, Anxiety, and Depression. Find top doctors who treat Severe or Chronic Depression near you in Auburn, IN. The. Federal Way-Auburn. Mine is not going so well. How Effective is SAINT TMS Therapy? While SAINT TMS therapy is relatively new, it has shown highly promising results for severe depression. Woodland, CA 95695. Haesebaert F, Moirand R, Schott-Pethelaz AM, Brunelin J, Poulet E. SAINT TMS was studied in 2020 at Stanford. In their report, they note initially that iTBS is approved by the US Food and Drug Administration (FDA) in treatment-resistant depression but is also limited by suboptimal efficacy and a six-week duration, with SAINT—a high-dose,. How. Transcranial Magnetic Stimulation (TMS) is a revolutionary treatment for mental health conditions that uses a. rTMS has excited the interest of clinicians and is highly acceptable to patients (Walter et al. Book an appointment today!Transcranial magnetic stimulation (TMS) is a safe, non-invasive treatment used to treat depression and other conditions in patients who have not found relief with standard treatments. top of page. SAINT promised that a more dense TMS protocol could be superior. Birmingham, AL Office (205) 968-1227. Objective: Depression is the leading cause of disability worldwide, and half of patients with depression have treatment-resistant depression. TMS works by sending magnetic pulses into a targeted area of the brain involved with mood regulation. March 25, 2022 • Research Highlight. Purpose of review. Call or Text us. com (650) 521-5211Major depressive disorder (MDD) affects approximately 10% to 15% of pregnant patients, causing maternal distress, increased risk of suicide, life-threatening obstetric complications, and lasting neurodevelopmental effects on offspring. It can stop you from functioning normally in your daily life. 17 hours ago · Ziegler has been out as he’s been having some battles with mental health. Prefrontal TMS therapy repeated daily for four to six weeks is a. S. The. , 2001), because of its ability to stimulate focal areas of brain cortex non. Here are some ways that may help you stay on top of things. A completed referral form is required prior to. Find the closest Greenbrook TMS center near you. It can treat depression, obsessive-compulsive disorder and other brain-related conditions. Transcranial magnetic stimulation (TMS) treats depression by targeting areas of low brain activity through noninvasive magnetic pulses. Wouldn’t it be great if we had a noninvasive method. Grass Valley, CA 95945. Adv Biol Psychiatry. 337 AIRPORT RD STE F, AUBURN, AL, 36830 . org. Does TMS Hurt. TMS Therapy gaining steam as depression treatment. 403 Kingsley Lake Drive. Some patients elect to go on to have maintenance treatment at less frequent intervals. The treatment schedule is also more robust than conventional TMS. Sessions typically last for 20-30 minutes, and the entire course of therapy requires weeks to complete. Transcranial Magnetic Stimulation has shown excellent results to relieve patients, but one of the chief downsides to conventional TMS has been the. After a series of treatments, the magnetic pulses. However, the methodological. Transcranial Magnetic Stimulation (TMS) is a game-changing, technological breakthrough in the treatment of Major Depression. Food & Drug Administration (FDA) for the SAINT™ Neuromodulation System for the. The Star Study shows that dTMS is highly effective at treating depression, with patients having a 67 percent remission rate compared to the 44 percent of patients who used rTMS. Insomnia. 9 weeks. 1%) achieve complete remission. In a study on 21. Clinical outcomes. Book an appointment today! The SAINT ™ neuromodulation system is a transcranial magnetic stimulation device that combines advanced imaging technologies with personalised targeting and novel stimulation patterns to deliver a new form of individualised neurostimulation to people with treatment-resistant depression. We then dive deep into the history, biology, modern use, and safety margins of the various psychedelics, including MDMA,. Question Is bilateral theta burst stimulation noninferior to standard bilateral repetitive transcranial magnetic stimulation (rTMS) in older adults with treatment-resistant depression?. S. Esketamine or S-Ketamine. They call it Stanford Accelerated Intelligent Neuromodulation Therapy or SAINT. 7405 Shallowford Rd. The researchers in the Stanford SAINT study achieved better results in a shorter time, getting 90. Thu, 09/22/2022 - 16:28. By Paula Dobbyn / March 6, 2023. Comprehensive care for depression and other mood disorders. TMS doesn't require anesthesia and it is generally. Repetitive transcranial magnetic stimulation (rTMS) is only considered medically necessary in adults who have a confirmed diagnosis of major depressive disorder (MDD), single or recurrent episode and meet the. Looking for a licensed mental healthcare professional in your area? Find your local LifeStance providers here. “SAINT is so innovative because it. It doesn't have any side effects associated with medicine. SAINT is different from current FDA-approved iTBS protocols in a few ways. Saint John's, NL . It will be available in late 2023. TMS can offer a lifeline for those whose depression does not respond to antidepressants. TMS is a non-drug, on-invasive, FDA cleared product that provides proven relief from depression, that lasts. Williams is a 2018 and 2016 BBRF Young Investigator and winner of the 2019 BBRF Klerman Prize for Exceptional Clinical Research. S. iTBS delivers a. REQUEST A CONSULTATION. The Food and Drug Administration (FDA) in September cleared the SAINT Neuromodulation System for the treatment of refractory depression in adults. Resting-state functional MRI was used to. It lacks providing a real drug-free alternative for severe depression treatment. Intermittent theta-burst stimulation, recently approved by the FDA for treatment-resistant depression, has significantly shortened the duration. Food and Drug Administration for the treatment of depression in. for treatment-resistant depression (TRD). Burlingame CA 94010 USA. Facebook Instagram (833) 867-2329 Transcranial magnetic stimulation, or TMS, is a noninvasive form of brain stimulation. TMS involves the administration of a small magnetic field over the left dorsolateral prefrontal cortex, one of the areas implicated in depression. A promising new treatment for depression 07:36. Uses fMRI targeting, figure 8 coil TMS, 10 treatments per day x 5 days. 3 people follow this. Formerly ABHC, the DiscoveryMD center in Bellevue, Washington, provides comprehensive services to treat mental health disorders. TMS is used for treatment-resistant Major Depressive Disorder often leading to complete remission from depression. (774) 307-7021. Low or high frequency transcranial magnetic stimulation (TMS) can be used. To learn more about TMS, Transcranial Magnetic Stimulation Therapy visit. Baystate Health offers TMS: In Baystate Medical Center's Psychiatric Neurotherapeutics unit in Springfield, MA ( 413-794-4584) At Baystate Wing Hospital's Griswold Behavioral Health Center in Palmer, MA ( 413-794-4584)The researchers’ optimism comes on the heels of an Oct. Elahi briefly discusses a monumental advancement in treatment of severe depression with transcranial magnetic stimulation (TMS). Williams and his colleagues have published the results of the RCT in The American Journal of Psychiatry. 125 130th ST SE, Suite 204 Everett, WA 98208 Phone: (425) 367-4949 Text: (425) 314-6913. Depression is a treatable illness, with standard treatments such as medication and lifestyle changes. Transcranial Magnetic Stimulation for Depression (October 2009, In Press, April 2011): The Blue Cross and Blue Shield Association performed an extensive literature review to evaluate the efficacy of transcranial magnetic stimulation for depression and. ☐Montgomery-Åsberg Depression Rating Scale (MADRS) ☐Patient Health Questionnaire Depression Scale (PHQ-9). July 27, 2022. In a study on 21 participants diagnosed with severe depression, SAINT caused 90 PERCENT TO EXPERIENCE RELIEF. (TMS) Depression is a mental health condition that can alter the way you feel and think. We have appointments available today. Transcranial Magnetic Stimulation (TMS) is an increasingly accepted neurostimulation- based treatment for major depressive disorder. SAINT or SNT stands for Stanford Accelerated Intelligent Neuromodulation Therapy. The first report of its effectiveness is very encouraging. Transcranial Magnetic Stimulation (TMS) is designed for adults, 18 years of age and older. You get personal time and space for relaxation, reflection, and recovery. Find top doctors who perform Depression Management near you in Auburn, ME. It uses an “electromagnetic coil” — a device that produces magnetic energy — to stimulate nerve cells in the part of the brain that controls mood. 149 13th. The Transcranial Magnetic Stimulation (TMS) clinic at Washington University offers this novel brain stimulation treatment for clinical depression. Sessions typically last around 30 minutes. It can stop you from functioning normally in your daily life. Neuromodulation Therapy (SAINT), an accelerated, high-dose resting-state functional connectivity MRI (fcMRI)– guided iTBS protocol for treatment-resistant depression. A SAINT (Stanford Accelerated Intelligent Neuromodulation Therapy) TMS Protocol Treatment Session is an innovative therapy for those suffering from severe depression. harvard. (423) 228-0579. Major depressive disorder (MDD) is now the leading cause of disability worldwide, with lifetime suicide rates as high as 15% (Friedrich, 2017; Lam et al. For the past 6 months I had a really bad infection after my surgery. 741 to −0.